Applications are sought for a Postdoc position for a collaborative project in the groups of Thomas Euler and Philipp Berens at the Institute for Ophthalmic Research, the CIN, and the Bernstein Centre for Computational Neuroscience (BCCN) of the University of Tübingen. The project is part of the DFG Priority Programme „Computational Connectomics” (SPP 2041).
The goal of the project is to combine functional imaging of excitatory and inhibitory signals with computational modeling based on connectomics data from electron microscopy to study the role of amacrine cell circuits in the retina.
Visual processing begins in the retina – here, within only two synaptic layers, more than 40 parallel channels emerge, which relay highly processed visual information to different parts of the brain. The origin of this vast functional diversity lies in the retina’s second synaptic layer, the inner plexiform layer, where bipolar cells, amacrine cells and ganglion cells form complex interconnected networks. In particular the amacrine cells, the most diverse class of retinal interneurons, are crucial for decorrelating different functional channels: They tune the ganglion cells’ responses, which represent the retina’s output, by modulating glutamate release from bipolar cells as well as heavily shaping the signal integration in the ganglion cell dendritic arbors. Despite decades of research, however, only a few amacrine cells circuits have been characterized in detail. We expect that our project will provide the most exhaustive account of the role of amacrine cells for visual processing to date.
What we are looking for:
The candidate for the position ...
● must have a PhD in a relevant discipline (e.g. neuroscience)
● must have experimental skills ideally in functional 2P imaging, alternatively in electrophysiology
● has a strong background in neuroscience at the circuit or systems level, ideally in the visual system
● is proficient in modern programming languages (i.e. Python)
● is experienced in data analysis.
The ideal candidate is self-motivated, independent, and able to learn quickly, is proficient in English verbal and written communication and has strong problem-solving skills.
What we offer:
The positions is available immediately, with funding for 3 years and possible extension depending on further funding. The postdoc will work embedded in an highly collaborative, interdisciplinary environment, providing ample possibilities for career development. We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The University of Tübingen promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.
How to apply:
Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to us.
You can also find this job offer for download here.
The information encoded by the brain during wakefulness in form of neural representations is reactivated during sleep, thus promoting its consolidation and long-term storage. While it was shown that repeated neural reactivations of hippocampal representations during sleep are essential for memory consolidation, it is not known whether and how do adult stem cells contribute to this process. Over recent years our laboratory has developed a modern toolkit enabling us to address this question (Kovalchuk et al., 2014, Liang et al., 2016).
Now we are looking for a motivated and talented PhD student interested in understanding how adult-born and mature granule cells in the hippocampal dentate gyrus contribute to memory consolidation during sleep. The student will team-up with other lab members and will learn/apply state‐of‐the art optical and electrophysiological techniques (in vivo two‐photon microscopy, the use of genetically-encoded calcium indicators, cell attached recordings, single cell electroporation, immunohistochemistry, etc.). The successful candidate can choose one of the two well structured training programs (Graduate school in Cellular & Molecular Neuroscience (http://www.neuroschool-tuebingen.de/master/cell-molec-neurosci) or PhD program in Experimental Medicine (https://www.medizin.uni-tuebingen.de/en/Research/Doctoral+Studies+at+the+MFT/PhD+Program+in+Experimental+Medicine.html).
Qualifications required: master’s degree in biology or medicine (ideally with focus on neuroscience). Previous laboratory experience in our research area (neuroscience, molecular biology, in vivo imaging) will be appreciated. In addition, candidates should be enthusiastic about learning new techniques and contributing to data collection and analysis. Good communication skills, ability to work in a team, and proficiency in English language are required.
Applications are welcome from overseas students as well as EU nationals. The application deadline is the 1st of December. The project starts in January 2018. Applications should include a detailed CV, a brief letter of motivation, and names of at least two reference persons. Please send these materials to Prof. Garaschuk (firstname.lastname@example.org). For further information about the lab please visit www.physiologie2.uni-tuebingen.de.
Find the job offer available for download here.
In January 2017, the collaborative research centre “Robust Vision – Inference Principles and Neural Mechanisms” (CRC 1233) started. Funded by the DFG (German Research Foundation), a group of more than 20 PIs will jointly address the question why biological visual systems are so remarkably robust. To this end, we will combine expertise in experimental and computational neuroscience, as well as in machine learning and computer vision.
As part of interdisciplinary collaborations within the CRC, 9 PhD and 2 Postdoc positions are available in different labs at the University of Tübingen.
1. One PhD position is available in the group of Philipp Berens at the Institute for Ophthalmic Research and the Center for Integrative Neuroscience (CIN) of the University of Tübingen. In collaboration with Laura Busse (LGN/V1 physiology, LMU Munich) and Thomas Euler (retinal imaging, University of Tübingen), the project will investigate transformations of representations between the retina and the dorsolateral geniculate nucleus (dLGN) of the thalamus.
Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to philipp.berensuni-tuebingen.de and add [CRC PhD Student] in the title. See also “General Information” below.
2. One PhD position is available in the lab of Frank Schaeffel at the Ophthalmic Research Institute. The project studies perceptual consequences of fixational eye movements and will be jointly supervised by Frank Schaeffel, Ziad Hafed at the CIN and Katharina Rifai at the Zeiss Vision Lab.
Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to frank.schaeffeluni-tuebingen.de. See also “General Information” below.
3. One Postdoc position is available in the lab of Ziad Hafed at the CIN. The research project represents a neurophysiological analysis of the visual consequences of fixational eye movements, using non-human primate neurophysiology and will be jointly supervised by Ziad Hafed, Frank Schaeffel and Katharina Rifai.
Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to ziad.m.hafedcin.uni-tuebingen.de. See also “General Information” below.
4. One PhD position is available in the group of Günther Zeck at the Natural and Medical Sciences Institute (NMI) at the University of Tübingen.
The project requires skills in neural engineering, interest in neural computations and the readiness to acquire the necessary experimental skills. Because of the interdisciplinary nature of the project, excellent collaboration and team skills are essential.
Applications should include a CV, a statement of research motivation and experience, and the names of two referees. Please compile your application in one single PDF-file and email it to guenther.zecknmi.de and add [CRC PhD Student] in the title. See also “General Information” below.
5. Two PhD positions are available in the lab of Hendrikje Nienborg at the Centre for Integrative Neuroscience (CIN) as part of two collaborative projects.
The position requires strong experimental and programming skills (ideally in Matlab or Python), and a background in neuroscience, computer science, electrical engineering, experimental psychology or a related field.
The second project is a collaboration between Hendrikje Nienborg and Karsten Rauss/Jan Born and examines sleep dependent signatures of perceptual learning. It combines high-density EEG recordings and fMRI in humans with wireless multichannel recordings in monkey visual cortex. The PhD student will be part of the team establishing the wireless recordings and responsible for the multichannel extracellular recordings and data analysis. The candidate will interact closely with a PhD based in the Born group responsible for the EEG and fMRI experiments in humans. The position requires strong engineering and experimental skills and a background in electrical engineering, computer science, neuroscience or a related field. Programming experience (ideally in Matlab or Python) will be highly valued.
Applications should include a CV, a brief statement of motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to hendrikje.nienborgcin.uni-tuebingen.de and add [CRC PhD Student] in the title. See also “General Information” below.
6. One Postdoc position and one PhD position are available in the lab of Markus Siegel at the Centre for Integrative Neuroscience (CIN) and MEG Center Tübingen.
Applications should include a CV, a brief statement of motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to markus.siegeluni-tuebingen.de. See also “General Information” below.
For the PhD position applications, eligibility for the PhD program is mandatory (a MSc degree or equivalent). Positions are immediately available, with funding for 3 years (with the option on a 1-year extension). We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The CRC promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.
The Werner Reichardt Centre for Integrative Neuroscience (CIN) is an interdisciplinary institution funded by the German Excellence Initiative program. The CIN strives to deepen our understanding of how the brain generates function and how brain diseases impair functions. Its scientific program is guided by the conviction that progress in the understanding of brain function can be achieved with an integrative approach spanning multiple levels of organization and pooling the knowledge of researchers from many different fields.
The Institute for Ophthalmic Research cooperates closely with the University Eye Hospital under the umbrella of the Centre for Ophthalmology. The Institute aims at uncovering the causes for degenerative, inflammatory, neoplastic, and vascular diseases of the eye and developing diagnostics and therapies based on these discoveries. Translational research is jointly performed with the University Eye Hospital Tuebingen.
Tübingen is a vibrant university city in the south of Germany. Besides the CIN, Tübingen is also home to the Hertie Institute for Cognitive Neurology and several institutes of the Max Planck Society, among others. This allows for a tremendous exposure to the latest advances in neuroscience, vision/robotics, human-computer interaction, brain-computer interfaces, etc. There are also opportunities for collaborative projects across labs/institutes.
The labs of Philipp Berens (www.berenslab.org) and Thomas Euler (www.eulerlab.de) at the Center for Integrative Neuroscience (CIN) at the Eberhard-Karls-University of Tübingen are offering a PhD position
(TV-L E13 65%)
to be filled as soon as possible, with funding for 3 years. We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The Eberhard-Karls-University of Tübingen promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.
The successful candidate will combine experimental and computational approaches to study neuronal cell type specific computations in the mouse retina. The goal of the project is to provide an account of how the functional response properties of selected ganglion cell types arise from their anatomical structure, connectivity and dendritic integration properties. We envision a highly interdisciplinary project, where the successful candidate will perform state- of-the-art optical imaging and electrophysiological recordings and use computational approaches to analyze their data.
The CIN offers a stimulating interdisciplinary scientific environment where research is carried out at all levels of neuroscience. The two labs are also part of the Institute for Ophthalmic Research (Eye Hospital Tübingen) and affiliated with the Bernstein Centre for Computational Neuroscience (BCCN).
Furthermore, the project will be performed in collaboration with the lab of Tom Baden at the University of Sussex, UK (www.badenlab.org).
- Background in statistics, machine learning and data analysis
- Experience with electrophysiology and/or two-photon imaging or a strong desire to learn these techniques
- Programming experience in Python, Matlab, R or similar
- Strong quantitative skills
Interested applicants should contact Dr. Philipp Berens (email@example.com) providing:
- a curriculum vitae
- a one-page description of past research experience & future research interests
- a one-page description of the motivation for applying to this position
- names of at least two people that could provide letters of reference
Please compile your application in one single PDF-file.
Click here to download the job offer as a PDF.
The newly established Andrea Burgalossi laboratory at the Centre for Integrative Neuroscience (CIN) is looking for PhD and Postdoc candidates.
Our lab investigates the cellular and synaptic basis of behaviour. We employ state-of-the-art methods developed in the Brecht lab (Lee et al., 2009; Burgalossi et al., 2011) to record intracellularly and juxtacellularly from single neurons in freely behaving animals, in combination with anatomical, molecular and optogenetic techniques. We use rodents (mice/rats) as model system, and focus primarily on the mechanisms by which external space is represented in the mammalian cortex.
The successful candidate will explore the circuit structure and synaptic mechanisms involved in spatial cognitive behaviours, and more generally in learning and memory. The candidate will join a team of young and enthusiastic members in the dynamic scientific environment of CIN.
Applications should contain a brief statement of research experience and interests, CV, and names of at least two referees. Please direct your application or any informal inquiries to research group leader Dr. Andrea Burgalossi. Applications should be sent electronically as a single PDF file.
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